Age

18–75

Sex

ALL

Healthy volunteers

Not accepted

Is hypersensitive to XIAFLEX or collagenase;
Is currently adjusting tone alternating medications (e.g., baclofen), or
Received botulinum toxin injection to target areas \<4 months, or phenol injections \< 9 months;
Received surgical release of tendons;
Is a pregnant woman;
Has coagulation disorders, including those who receive concomitant anticoagulants (except for low-dose aspirin).
has heritable connective tissue disorders, including those within the Ehlers-Danlos syndrome (EDS) spectrum.

Collagenase Injection for Contracture Management