Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Ache Laboratorios Farmaceuticos S.A.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Participants of either sex, aged ≥18 years;
Participants diagnosed with ocular hypertension or primary open-angle glaucoma according to the Clinical Protocol and Therapeutic Guidelines for Glaucoma;
Participants requiring ocular hypotensive treatment in one or both eyes, for whom the use of combination topical ocular hypotensive medications is appropriate for intraocular pressure (IOP) reduction.
You may not be if
Participants diagnosed with primary open-angle glaucoma with no prior treatment history for the disease;
Participants with a cup-to-disc ratio \>0.8 (horizontal or vertical);
Participants with any other clinically significant ocular disease that, in the investigator's opinion, may interfere with the evaluation of study efficacy and safety variables;
Participants with ocular infection or inflammation within 3 months prior to the screening/run-in visit;
Participants with a history of trabeculoplasty (within the last 6 months) or surgical procedures for IOP reduction;
Participants with a history of ocular surgery within 6 months prior to the screening/run-in visit;
Participants with any corneal abnormality that may affect IOP measurement;
Participants with respiratory or pulmonary disorders, such as asthma or chronic obstructive pulmonary disease (COPD);
Participants with the following cardiac conditions: sinus bradycardia, sinoatrial block, second- or third-degree atrioventricular block, overt heart failure, or cardiogenic shock;
Participants with uncontrolled systemic diseases, such as diabetes, hypertension, chronic hepatic or renal disorders, or any other medical condition that, in the investigator's opinion, may interfere with the investigational product or comparator.
