Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical Technique

Exclusion Criteria

• •1. Patients with systemic diseases.
• •2. Pregnant or lactating females.
• •3. Tobacco smokers (≥ 10 cigarettes per day).
• •4. Multi-rooted teeth with class II and class III furcation defects.
• •5. Third molars.
• •6. Teeth with grade III mobility.
• •7. Peri-apical pathology and acute abscess.
• •8. Non-surgical or surgical periodontal treatment in the past 12 months.
• •9. Prolonged treatment with antibiotics or anti-inflammatory agents within 6 months before periodontal therapy.