A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies

Exclusion Criteria

• •1. Presence of gastrointestinal obstruction preventing oral intake at screening/enrollment
• •2. Use of immunosuppressants at screening/enrollment
• •3. Life expectancy ≤ 3 months
• •4. Presence of malabsorption syndrome or any condition affecting gastrointestinal absorption, e.g., chronic diarrhea (watery stools; daily stool frequency ≥ 5 times)
• •5. Patients planning pregnancy, pregnant, or breastfeeding
• •6. Known allergy to any component of the investigational products
• •7. Presence of severe primary diseases of the heart, brain, lung, liver, kidney, endocrine, blood, nervous systems or other acute/chronic diseases that could significantly affect treatment and prognosis
• •8. Presence of other severe physical or mental illnesses or laboratory abnormalities that may increase the risk of participating in the study, or patients deemed unsuitable for the study by the investigator