Lead Sponsor

First Affiliated Hospital, Sun Yat-Sen University

Age

All ages

Sex

ALL

Healthy Volunteers

No

•Clinical diagnosis of scar requiring therapeutic intervention, including but not limited to hypertrophic scar, keloid, atrophic scar, postoperative linear scar, burn scar, post-traumatic scar, or post-acne scar.
•Scar duration ≥ 3 months, in stable or proliferative phase.
•Age ≥ 12 years (for minors under 18 years, informed consent must be provided by a parent or legal guardian).
•Stable vital signs and able to tolerate scar treatment.
•Understand and willing to participate and able to provide signed informed consent.

•Active infection, ulceration, or malignant tumor involving the scar area. Severe uncontrolled systemic disease or major organ dysfunction (heart, lung, brain, etc.).
•Psychiatric disorder that prevents compliance with treatment.
•Presence of diseases (malignant tumor, autoimmune disease) or use of medications (high-dose corticosteroids: ≥40 mg prednisone or equivalent per day for ≥2 weeks) that may affect scar healing or assessment.
•HIV positivity, clinical diagnosis of AIDS, or absolute neutrophil count (ANC) \< 1000 cells/mm³ during screening.
•Pregnancy or breastfeeding.
•Previous treatment of the scar area (e.g., laser, injection, surgery) without a washout period of ≥3 months.