Trial to Demonstrate the Equivalence of Two Different Strengths of Oral Centanafadine Capsules in Healthy Subjects

Exclusion Criteria

• •1. Clinically significant abnormality in past medical history, or at the screening physical examination, that in the investigators or sponsor's opinion may place the participant at risk or interfere with outcome variables including absorption, distribution, metabolism, and excretion of drug.
• •2. History of drug and/or alcohol abuse within 2 years prior to screening.
• •3. History of or current hepatitis or acquired immunodeficiency syndrome (AIDS) or carriers of hepatitis B surface antigen (HBsAg) and/or hepatitis C antibodies (anti-HCV), or human immunodeficiency virus (HIV) antibodies.
• •4. History of any significant drug allergy or known or suspected hypersensitivity.
• •5. Participants having taken an investigational drug within 30 days prior to screening.
• •6. Previous exposure to centanafadine.
• •7. Any history of significant bleeding or hemorrhagic tendencies.
• •8. A history of difficulty in donating blood.
• •9. The donation of blood or plasma within 30 days prior to the first dose of investigational medical product (IMP).
• •10. Use of prescription, over-the-counter, herbal medication or vitamin supplements within 14 days prior to the first dose of IMP and antibiotics within 30 days prior to the first dose of IMP.