Diagnostic Performance and Safety of Endobronchial Ultrasound-guided Transbronchial Mediastinal Cryobiopsy in Diagnosing Tuberculous Mediastinal Lymphadenitis: a Randomised Controlled Trial

Exclusion Criteria

• •Known allergy to lidocaine or midazolam;
• •Presence of bronchial artery penetration into the target lesion or high risk of bleeding as detected by contrast-enhanced CT or EBUS Doppler mode prior to the procedure;
• •Unstable angina, congestive heart failure, or severe bronchial asthma;
• •Evidence of significant liquefaction necrosis in the target mediastinal lymph node on pre-procedural CT or EBUS;
• •Patient refusal to participate in the study;
• •Participation in another clinical trial within the past three months that may interfere with the outcomes of this study;
• •Any other condition that, in the opinion of the investigator, makes the patient unsuitable for study participation