Implanted PA pressure sensors enable early detection of heart failure decompensation but are costly and invasive. Fluid retention in heart failure may affect the vocal apparatus, producing measurable voice changes that could serve as a non-invasive alternative for monitoring pulmonary congestion.
Participants record daily voice samples consisting of sustained vowel sounds and a standardized reading passage via the Noah Labs mobile app. PA pressure readings are collected daily per standard care. Voice recordings and clinical data are analyzed retrospectively using classical machine learning and deep learning approaches. No additional clinical visits are required.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18 years or older
Successful implantation of a PA pressure sensor and monitored by a participating study center
Willingness to record a short predefined text daily for 3 months using a smartphone or tablet
Ability to comfortably read aloud the study passage in English or German
Written informed consent obtained
You may not be if
Pregnant, breastfeeding, or unwilling to practice birth control during participation
Condition that in the opinion of the investigator would compromise patient safety or data quality
Pathological voice changes due to surgery or injury
Planned invasive cardiac procedures during the study period
COPD requiring home oxygen therapy
Chronic kidney disease requiring dialysis
Cognitive dysfunction limiting ability to perform daily voice recording
