Biventricular or Left Bundle Branch Pacing to Assess the Effect of Cardiac Resynchronization Therapy in Patients Undergoing Transcatheter Aortic Valve Implantation

Exclusion Criteria

• •Pre-existing right bundle branch block, or prior pacemaker/ICD implantation associated with significant (\>20%) ventricular pacing
• •* Progression of LBBB during hospitalization to a degree indicating pacemaker implantation (e.g., Mobitz II or third-degree AV block, alternating bundle branch block) before the planned discharge date
• •* Concomitant severe valvular disease of other valves (mitral, pulmonary, or tricuspid)
• •* Severe infection and/or septic state
• •* TAVI-associated stroke
• •* More than moderate paravalvular leak of the TAVI valve on postoperative echocardiography
• •* EF \< 35% or \> 55% on echocardiography performed at the planned time of discharge
• •* GOLD stage IV COPD
• •* Chronic renal failure requiring regular dialysis
• •* Concurrent participation in another clinical trial