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Continued Pressure for Alveolar Protection (CPAP Trial)

NCT07417111·15 sites·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Colm P. Travers, MD
CONTACT
205-934-3100 [email protected]
Abhik Das, PhD
CONTACT
301-230-4640 [email protected]

Lead

NICHD Neonatal Research Network

With

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Age

0–0

Sex

ALL

Healthy volunteers

Not accepted

You may be eligible if

Gestational age \<29 weeks at birth
PMA \<32 weeks at study entry
On treatment with CPAP without a rate in FiO2 \<0.25 and PEEP of 4-5 cmH2O
Meet stability criteria:
If previously intubated must be extubated ≥ 72 hours
\<3 self-resolving apneas (≤ 20 s) and/or bradycardia (\<100 bpm) in any hour over previous 6 hours
No episodes of apnea or bradycardia requiring intervention (oxygen/stimulation/bag and mask) for 24 hours
Parents/legal guardians consent for enrollment

You may not be if

Major malformation
Neuromuscular condition that affects respiration
Terminal illness
Decision to withhold or limit support
Too sick to participate in opinion of Attending physician
Clinical shock, sepsis
Planned surgery during study period

The record

StatusRecruiting

PhaseNo phase

Taking part860

StartedNov 2026

UpdatedJul 14, 2026

Conditions

Bronchopulmonary Dysplasia (BPD)

Where15

University of Alabama at Birmingham
Birmingham, Alabama, United States
Stanford University
Palo Alto, California, United States
Sharp Mary Birch Hospital for Women & Newborns
San Diego, California, United States

Clareo Health | Continued Pressure for Alveolar Protection (CPAP Trial)