Study of Lesion-Specific Invasive Haemodynamic Angina Thresholds

Inclusion Criteria

• •1. Eligibility for PCI due to angina or angina-equivalent symptoms on exertion
• •2. 2 severe epicardial stenoses in a major coronary artery, defined as:
• •1. ≥70% stenosis in a coronary artery with ≥2.5mm diameter, on invasive coronary angiography (ICA)
• •2. Severe stenosis in a vessel with ≥2.5mm diameter, on CTCA
• •3. Evidence of ischaemia on an invasive or non-invasive test, including:
• •1. Physiological test during invasive coronary angiography (ICA)
• •2. Dobutamine stress echocardiography (DSE)
• •3. Stress perfusion cardiac magnetic resonance (CMR)
• •4. Myocardial perfusion scintigraphy (MPS)
• •5. Fractional flow reserve computed-tomography (FFR-CT)