Comparing XEN®-63 Gel Stent and PRESERFLO® MicroShunt

Exclusion Criteria

• •An established diagnosis of: Closed-angle glaucoma or Secondary open-angle glaucoma (besides PDG and PEX)
• •Lens status: Aphakic patients or Anterior chamber intraocular lens
• •Previous procedures: Glaucoma shunt/valve/ surgery or cyclodestructive procedure, Selective laser trabeculoplasty within the past 3 months, Incisional ophthalmic surgery involving the conjunctiva within the past 3 months, Clear corneal cataract or trabecular meshwork surgery conducted within the past 6 months.
• •Presence of intraocular silicone oil
• •No light perception vision
• •Current corticosteroid use (ocular or oral)
• •Conjunctival pathologies (e.g., pterygium)
• •Active inflammation (e.g., blepharitis, conjunctivitis, keratitis, uveitis)
• •Vitreous present in the anterior chamber
• •Active iris neovascularization or neovascularization of the iris within 6 months of the surgical date
• •Unwillingness or inability to give consent, accept randomization or return for and participate in scheduled protocol visits