Shanghai Municipal Hospital of Traditional Chinese Medicine
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Age
Any age
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Patients with a clinical diagnosis of Parkinson's disease (PD) according to the \_Chinese Diagnostic Criteria for Parkinson's Disease (2016 edition)\_.
2. Willingness to undergo biospecimen collection, including cerebrospinal fluid (optional), blood, and saliva, and to complete neuroimaging examinations (MRI, PET/SPECT) and disease-specific clinical assessments.
3. Provision of written informed consent
1. Patients with a clinical diagnosis or clinically probable multiple system atrophy (MSA) according to the Chinese Expert Consensus on the Diagnostic Criteria for MSA (2022).
2. Willingness to undergo biospecimen collection, including cerebrospinal fluid (optional), blood, and saliva, and to complete neuroimaging examinations (MRI, PET/SPECT) and disease-specific clinical assessments.
3. Provision of written informed consent.
You may not be if
1. Patients with an unclear or uncertain diagnosis.
2. History of stroke, head trauma, hydrocephalus, brain tumor, intracranial hypertension, or intracranial surgery.
3. Evidence of intracranial organic lesions on CT/MRI.
4. Severe anxiety, depression, or schizophrenia.
5. Severe comorbidities involving the heart, lungs, liver, kidneys, endocrine system, or hematological system.
6. Presence of aphasia, severe dysarthria, or other conditions that significantly impair clinical assessments.
7. Anticipated poor compliance.
Clareo Health | Shanghai Clinical Cohort - Parkinson's Disease (Reserve)
