Investigating the Effects of Intermittent Hypoxia-Hyperoxia Treatment (IHHT) in People With Post-Viral Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) to Improve Fatigue, Pain, and Quality of Life by Targeting Mitochondrial Dysfunction and Autonomic Nervous System Impairment

Inclusion Criteria

• •Eligibility Criteria ME/CFS Patients
• •Established diagnosis of ME/CFS according to the International Consensus Criteria (ICC)
• •Presence of post-exertional malaise (PEM)
• •Disease duration \> 6 months
• •Mild or moderate disease severity according to NICE guidelines
• •Ability to attend clinic visits for inclusion and IHHT intervention
• •Female sex
• •Age 20-59 years
• •Ability to attend clinic visits
• •Female sex
• •Age 20-59 years
• •BMI matched to ME/CFS participants
• •Activity level matched to ME/CFS participants