Effectiveness of a Sodium Hyaluronate 0.01% and Sh-Oligopeptide-85 SP Mouthwash for the Treatment of Symptomatic Oral Lichen Planus

Exclusion Criteria

• •1. Pregnant or breastfeeding women.
• •2. Allergy to the components of the Tectum-11® mouthwash.
• •3. Patients receiving corticosteroids, immunosuppressants, hydroxychloroquine, or retinoids at the time of recruitment.
• •4. Patients with lichenoid lesions: drug-induced lichenoid reactions, contact lichenoid lesions, or graft-versus-host disease.
• •5. Use of topical corticosteroids within the previous 4 weeks or systemic treatment within the previous 8 weeks.
• •6. Use of other mouthrinses for plaque control.
• •7. Patients unwilling to sign the informed consent form.
• •8. Patients with a VAS score \> 6.
• •The presence of any of the following criteria will lead to withdrawal of the participant from the study:
• •1. Failure to attend follow-up visits.
• •2. Occurrence of adverse events deemed clinically relevant by the investigator.
• •3. The patient reports that they no longer wish to participate in the study.
• •5. Non-adherence to the treatment regimen, defined as failure to follow the protocol for more than two consecutive weeks.