Lead Sponsor

Neomente SAS

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

•1. Being male or female, aged 18-65.
•2. Having a current DSM-5 diagnosis of non-psychotic Major Depressive Disorder confirmed by SCID.
•3. Having moderate to severe depressive symptoms as measured by the HAM-D-17.
•4. Being indicated for pharmacotherapy for Major Depressive Disorder.
•5. Providing written informed consent (signed and dated).
•\-

•1. Having a current or past diagnosis of bipolar disorder or psychotic disorders.
•2. Having a moderate to severe substance use disorder within the past six months.
•3. Having active suicidal ideation.
•4. Having a neurocognitive disorder.
•5. Having an unstable or decompensated medical illness likely to confound study outcomes.
•6. Being pregnant or lactating.
•7. Having known contraindications to the indicated antidepressant classes.
•8. Being unable to provide informed consent.
•\-

Related studies

NCT06793397 · Major Depressive Disorder (MDD), Depression in Adults, and more

NCT06878859 · Depression - Major Depressive Disorder, Cannabis Use Disorder, and more

NCT07422519 · Depression - Major Depressive Disorder, Depression Disorder, and more

NCT07424781 · Depression - Major Depressive Disorder, Irritability, and more

NCT07404085 · Bipolar Disorder (BD), Depression - Major Depressive Disorder, and more

BIOMARKERS FOR DRUG SELECTION IN DEPRESSION