Comparison of the Amplatzer Amulet Versus LAmbre Device for Left Atrial Appendage Closure

Exclusion Criteria

• •Patient life expectancy \<1 year (terminal illness).
• •Patient with requirement for oral anticoagulation therapy for any indication other than non-valvular atrial fibrillation.
• •Patient with prior surgical ligation or obliteration of the left atrial appendage.
• •Patient with history of allergic reaction or intolerance to any material used in the study devices or to any of the antithrombotic agents required post-procedure.
• •Patient with active systemic infection.
• •Patient with concurrent participation in another investigational study that may affect study results.
• •Patient with inability or unwillingness to comply with the study protocol or follow-up requirements.
• •Patient pregnant or breastfeeding women.