Multimodal Prediction of Response to Chemoradiotherapy for Squamous Cell Carcinoma of the Head and Neck

Exclusion Criteria

• •Head and neck squamous cell carcinomas in other locations (salivary gland, larynx, hypopharynx, cavum, sinuses)
• •Primary squamous cell carcinoma of the lymph nodes
• •History of radiotherapy to the head and neck region
• •Radiochemotherapy not based on the use of cisplatin
• •Pregnant or breastfeeding women
• •History of invasive cancer in the last 3 years (except for Breslow melanoma less than 1 mm)
• •Contraindication to MRI, CT, or PET/CT
• •Allergy or contraindication to iodine, gadolinium, or 18F-FDG
• •Uncontrolled diabetes (fasting blood glucose greater than 12 mmol/l)
• •Patients unable to understand the study for any reason or to comply with the trial requirements (language, psychological, geographical issues, etc.)
• •Patients under guardianship or conservatorship
• •Patients deprived of their liberty by judicial or administrative decision
• •Patients undergoing psychiatric care that renders them incapable of giving their consent
• •Patients admitted to a health or social care facility for purposes other than research