PRIMA-HF: Predicting Myocardial Recovery in Heart Failure Using Cardiac Imaging HAI-HF: High Dosing vs. Standard Dosing Adenosine During Myocardial Perfusion in Heart Failure

Exclusion Criteria

• •Previous diagnosis of heart failure
• •Unable to understand the patient information
• •Pregnancy, as the study involves ionizing radiation.
• •Current severe valvular disease (as defined by the Danish national treatment guidelines on cardio.dk)
• •Atrial fibrillation with a heart rate \> 130 beats per minute during the inclusion echocardiography
• •Cardiac surgery within 6 months prior to inclusion
• •Acute exacerbation of existing chronic obstructive pulmonary disease
• •Severe asthma or chronic obstructive pulmonary disease with FEV1 \< 1L
• •any contraindication for adenosine stress testing
• •Severe renal failure \< 15 mL/min/1.73m² or dialysis
• •Advanced liver disease (Child-Pugh class C)
• •Endocarditis at inclusion/baseline
• •Isolated right-sided heart failure
• •Malignant disease treated with chemotherapy or radiotherapy, or expected life expectancy under 1 year