TC-G203 for Patients With GPC3-Positive Advanced Solid Tumors

Exclusion Criteria

• •1. Primary CNS malignancy or uncontrolled CNS metastases.
• •2. Other malignancies within 5 years
• •3. Active autoimmune disease or history of autoimmune disease.
• •4. Immunodeficiency, including HIV positivity
• •5. Bleeding disorders (inherited or acquired).
• •6. Clinically significant cardiovascular disease.
• •7. Active infection (including tuberculosis, hepatitis C, syphilis).
• •8. Pregnant or breastfeeding women.
• •9. Severe systemic or psychiatric illness.
• •10. Prior cell or gene therapy.
• •11. Severe drug hypersensitivity history.
• •12. Investigator-assessed unsuitability for trial participation. -