Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The Third Xiangya Hospital of Central South University
Age
30–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Aged ≥30 and \<80 years, regardless of gender;
2. Confirmed diagnosis of hypertension meeting the criteria outlined in the 2024 Chinese Hypertension Guidelines: office blood pressure ≥140/90 mmHg and home blood pressure ≥135/85 mmHg;
3. Mild to moderate hypertension, with office blood pressure ranging from 140-179/90-109 mmHg;
4. No prior use of antihypertensive medications;
5. Voluntary participation in the study with written informed consent obtained.
You may not be if
1. Diagnosed or highly suspected secondary hypertension;
2. Classified as mixed type according to hemodynamic typing;
3. Allergy to the intended antihypertensive medications;
4. Dysphagia;
5. Pregnant or lactating women;
6. Potential pregnancy plans during the trial period;
7. Uncorrected electrolyte disturbances;
8. Severe organ dysfunction;
9. Comorbid conditions leading to inaccurate blood pressure measurement;
10. Comorbid conditions or states unsuitable for noninvasive hemodynamic measurement via bioelectrical impedance;
11. Comorbid conditions contraindicating or requiring caution with trial medications;
12. Comorbid conditions affecting the absorption, distribution, metabolism, or excretion of trial drugs;
13. Concurrent or planned use of medications contraindicated or requiring caution with trial drugs;
14. Concurrent or planned use of medications interfering with trial outcomes;
15. Clinician's assessment deems the patient unsuitable for the trial's antihypertensive regimen;
16. Current participation in other clinical studies that may interfere with the conduct of this trial.
Clareo Health | Antihypertensive Drug Selection Based on Hemodynamic Phenotypes
