Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
With
University of Ulm
University Of Perugia
University of Eastern Finland
Martin-Luther-Universität Halle-Wittenberg
Sociodemographic studies in mental disorder (MD) and neurodegenerative diseases (ND). Sociodemographic factors increase the likelihood of developing an MD and contribute to poorer outcomes. There is less research on socioeconomic differences in ND, but also low socioeconomic status is also associated with dementia risk and early onset dementia. Substantial gaps remain in understanding the social and biological mechanisms underlying these disparities. Effective public health interventions to reduce the burden of these disorders are currently lacking.
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age\>18 and donation of blood,
full clinical and psychological assessment
Available neuroimaging is optional as not all patients are suitable.
Age and sex-matched unaffected volunteers without a MD or ND diagnosis are used as controls.
Unaffected controls are usually spouses or children of patients that are informed about our studies at each clinical site.
You may not be if
Lack of neuropsychological data,
anticoagulant treatment such as acenocoumarol, heparin, warfarin, dabigatran, rivaroxaban, apixaban, drug abuse in the last year,
medical history of cancer affecting the central nervous system that has not been in complete remission for 5 years or longer,
the patient has received potentially neurotoxic chemotherapy and/or patient has received cranial radiotherapy.
Clinical diagnosis of Alzheimer's disease where pathophysiological markers (measured in CSF or plasma) are inconsistent with Alzheimer's disease pathophysiology.
Cognitively healthy volunteers where pathophysiological markers (measured in CSF or plasma) are consistent with Alzheimer's disease or other neurodegenerative pathophysiology.
Clareo Health | Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
