Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Delivery of Interventions:
* Administration of a single kisspeptin bolus in a dosing range of 0.313 - 13.19 μg/kg
* Blood sampling before and after administration of kisspeptin (two timepoints total)
Age
18–60
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Female (ages 18-45 years) or Male (ages 18-60 years)
No current or recent use of a medication (including hormonal replacement) that, in the opinion of a study investigator, can modulate the reproductive axis or willing to complete an appropriate washout for that particular medication and its method of administration
For women, negative serum hCG pregnancy test
For cases, diagnosis of post-covid-19 syndrome
For controls, history of prior covid infection but no diagnosis of post-covid-19 syndrome
You may not be if
Any condition (medical, mental, or behavioral) that, in the opinion of a study investigator, would likely interfere with participation in/completion of the protocol or the interpretation of results
Active use of illicit drugs (not including marijuana)
For women,
Pregnant
Trying to become pregnant during protocol participation
Breast feeding
Surgical or natural menopause
Clareo Health | Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease