Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

Exclusion Criteria

• •Bilateral strokes (infarcts and/or hematoma)
• •Other co-existent neuromuscular disorders affecting upper extremity motor impairment
• •History of medically uncontrolled depression or other neuropsychiatric disorders despite medications either before or after a stroke that may affect the subject's ability to participate in the study
• •History of confirmed dementia or taking dementia drugs
• •Uncontrolled hypertension despite medical treatment(s) at the time of enrollment, defined as SBP≥185 mmHg or DBP≥110 mmHg (patient can be treated, reassessed and enrolled later)
• •Presence of any MRI/TMS/LIFUS risk factors
• •Concurrent enrollment in another interventional stroke recovery study
• •Concerns that the subject cannot comply with study procedures and visits
• •Pregnant