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RECRUITINGPhase 1NCT07199270

A Study to Evaluate the Safety, Immunogenicity, and Pharmacokinetics of GR2303 in Healthy Adult

he goal this clinical trail is to evaluate the safety、Pharmacokinetic and immunogenicity of GR2303 injection。 Subjects will be enrolled in different groups in sequential order, and within each group w...

Lead sponsor: Genrix (Shanghai) Biopharmaceutical Co., Ltd.•1 locations•View source on ClinicalTrials.gov

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Contacts

Nian

CONTACT

021-50805989-08324 [email protected]

Sponsors

Lead Sponsor

Genrix (Shanghai) Biopharmaceutical Co., Ltd.

This is a randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and preliminary pharmacodynamic profile of GR2303 Injection in healthy adult Chinese subjects. After signing the informed consent form, subjects who meet the criteria for enrollment will be entered into different groups according to the randomization number. Subjects will be enrolled in only one of these groups.

Age

18 - 45 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Healthy adult subjects
•2. Signed informed consent

Exclusion Criteria

•1. History or presence of any clinically significant organ system disease that could interfere with the objectives of the study or the safety of the subjects.
•2. Prior use of drug targeting TNF-like cytokine 1A
•3. history of malignant tumor
•4. psitive results for Hepatitis B surface antigen (HBsAg), anti Hepatitis C antibody (HCV Ab) or human immunodeficiency virus (HIV)

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 30, 2025Terms

Trial snapshot

StatusRECRUITING

PhasePHASE1

Enrollment64

Start dateSep 2025

Last updatedSep 30, 2025

Condition

Health Adult Subjects

Locations shown

Beijing Friendship hospital, Capital Medical University

Beijing, Beijing Municipality

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 30, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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