Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4

Exclusion Criteria

• •Patients with an MRI-incompatible device or implant (e.g. pacemakers, stents)
• •Preterm infants less than 25 weeks postmenstrual age (PMA) at the time of the scan.
• •Patients who are clinically too unstable to extend their MRI by up-to 10 minutes.
• •Patients who do not require clinical anesthesia.
• •Patients at risk for propofol infusion syndrome (known severe metabolic acidosis, hyperkalemia, lipemia, rhabdomyolysis, hepatomegaly, renal failure, ECG ST segment elevation, and/or cardiac failure)
• •Patient at risk for sensitivity to volatile halogenated anesthetic agents (known congenital Long QT Syndrome or patients taking drugs that can prolong the QT interval),
• •Patients with Perioperative Hyperkalemia (known neuromuscular disease, particularly Duchenne muscular dystrophy)