Up to date with CRC screening colonoscopy with a high risk of CRC, defined as a history of 3 or more adenomatous polyps (APs) or an AP \>1 cm in the past 5 years
Identify as Black or Non-Hispanic White
If female, no menstrual period for at least six months
Willingness to donate oral wash and stool samples
Willingness to complete 24-hour dietary recalls
You may not be if
Antibiotic use within the last 6 months
Abnormal gastrointestinal transit
A history of organ transplantation
Use of illicit drugs, combustible tobacco, or dietary supplements
Pre- or probiotics within the last two months
A history of cancer treatment within the past 12 months
CRC or a genetic predisposition to CRC
A baseline body weight \> 450 lbs
Weight gain or loss \> 4 kg 3 months prior to study
Significant food allergies, food preferences or therapeutic or vegetarian diets
Menstrual cycle within the last 6 months
Antibiotics in the last 2 months
Cannot keep a food record for 7 consecutive days during screening after detailed instruction
Significant medical conditions
History of eating disorders
Alcoholism
Individuals under the age of 18
Clareo Health | The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities