National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Age
0–17
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Age \>1 month and \<18 years
2. Weight \>5kg and \<50kg
3. Vancomycin intended duration of therapy ≥48 hours
4. Admitted to intensive care unit with suspected or confirmed sepsis
5. Either sepsis-induced respiratory (invasive mechanical ventilation) or cardiovascular (vasoactive infusion) dysfunction as part of sepsis-associated organ dysfunction (these organ dysfunctions may be improving or resolved at the time of enrollment)
You may not be if
1. Serum creatinine elevated and meets criteria for trough-based dosing by local Clinical Pharmacy
