Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia

Exclusion Criteria

• •History of ibuprofen allergy
• •Active erosive or ulcerative lesions of the gastrointestinal tract
• •Chronic use of opioid analgesics or NSAIDs prior to enrollment
• •Chronic kidney disease ≥ 3b stage according to the KDIGO classification
• •Liver dysfunction (three times exceeding the upper reference limit of ALT or AST)
• •A history of bronchial asthma
• •A history of hereditary coagulopathies
• •A history of use of anticoagulants