Effect of Exercise on Tapering Antipsychotics in Patients With Psycho-cardiological Disease(EXTRA-study)

Exclusion Criteria

• •1. currently has mania or hypomania, or a history of bipolar disorder and any mental disorders (current and previous);
• •2. organic brain injury, etc., or serious non-cardiovascular system diseases (such as advanced cancer);
• •3. Unable to participate in sports training or have drug contraindications;
• •4. Current alcohol, drug abuse, drug use or suicidal intent;
• •5. Patients who were receiving other doses of eligible drugs and other antidepressants were excluded from the trial;
• •6. Myocardial infarction \<2 weeks or unstable angina attack period;
• •7. Severe and uncontrolled arrhythmia;
• •8. Acute heart failure stage;
• •9. Severe and symptomatic obstruction of the outflow tract;
• •10. Acute deep vein thrombosis with or without pulmonary embolism;
• •11. Acute myocarditis, pericarditis or endocarditis;
• •12. Acute aortic dissection;
• •13. Intracardiac thrombus with high risk of embolism;
• •14. Massive pericardial effusion;
• •15. Those who fail to exercise adequately or refuse to sign informed consent.