Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia

Exclusion Criteria

• •Structural lesion in Upper GI endoscopy and/or positive CLO test
• •Patients scoring 1 or 2 on the 5-point Likert scale for all four dyspepsia symptoms
• •History of malignancy, significant liver and biliary tract disease, hypertension, diabetes mellitus, chronic kidney disease, thyroid disorder, major psychiatric disorders
• •Previous history of gastrointestinal surgery
• •Patients those have to take any drug for other medical condition that may cause dyspepsia
• •Any patient with ongoing treatment with antidepressants or antipsychotics
• •Any history of hypersensitivity, adverse effect, or ineffectiveness with amitriptyline or trifluoperazine
• •Patients for whom Amitriptyline and Trifluoperazine are contraindicated
• •Elderly patients\> 60 years
• •Pregnancy and breastfeeding