[68Ga]Ga-PSMA PET/CT in Hepatocellular Carcinoma: Impact of Multiparametric Dynamic Whole-body Imaging and Kinetic Modeling.

Exclusion Criteria

• •1. Known hypersensitivity to PSMA-11, to any excipient or derivative or to radiographic contrast agents
• •2. Patient requiring emergent surgery for a ruptured / bleeding HCC
• •3. Radioembolization within 3 months prior to inclusion
• •4. Cardiac disease with New York Heart Association classification of III or IV
• •5. Any major surgery within 4 weeks before enrollment
• •6. Other known malignancies (except for fully-resected non-melanoma skin cancer or cervical cancer in situ) unless definitively treated and proven no evidence of recurrence for 2 years
• •7. Any uncontrolled significant medical, psychiatric or surgical condition (active infection (subjects with known human immunodeficiency virus (HIV) positive)), unstable angina pectoris, cardiac arrhythmia, poorly controlled hypertension, poorly controlled diabetes mellitus (glycated haemoglobin (HbA1c) ≥9%), uncontrolled congestive heart disease, etc.) or laboratory findings that, in the opinion of the investigator, might jeopardise the subject's safety or that would limit compliance with the objectives and assessments of the study
• •8. Woman who are pregnant or breastfeeding. A serum pregnancy test will be performed at the start of the study for all female subjects of childbearing potential
• •9. Patient under guardianship or trusteeship
• •10. Patient under judicial protection