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CKD Cachexia and Gut Microbiome | Clinical Trials | Clareo Health

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RECRUITINGNCT06986265

CKD Cachexia and Gut Microbiome

Cachexia is common in patients with chronic kidney disease (CKD) and is associated with increased morbidity and mortality. Cachexia is a complex syndrome, in which inflammation and retention of uremic...

Lead sponsor: Université Catholique de Louvain•2 locations•View source on ClinicalTrials.gov

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Contacts

Laure Bindels, PhD

CONTACT

+32(2)7647337 [email protected]

Eric Goffin, MD

CONTACT

+32(2)7641855 [email protected]

Sponsors

Lead Sponsor

Université Catholique de Louvain

Collaborators

Fonds National de la Recherche Scientifique
FRC- Fonds de la Recherche Clinique
SFNDT - Société Francophone de Néphrologie, Dialyse et Transplantation

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age ≥ 18 years
•Diagnosis of kidney failure (stage V)
•Maintenance dialysis for at least 3 months
•Understanding of the trial procedures and ability to adhere to the trial protocol

Exclusion Criteria

•Severe nonadherence to the dialysis procedure
•Life expectancy below 1 year
•Chronic inflammatory disease of the digestive tract (Crohn's disease, ulcerative colitis)
•Bariatric surgery
•Active cancer
•Pregnancy
•Antibiotics consumption in the month preceding the inclusion
•Gastro-intestinal surgery, colonoscopy, or probiotics consumption in the 3 months preceding the inclusion
•Drugs influencing body composition initiated ≤ 1 month : systemic corticosteroids, anabolic drugs as insulin or testosterone, post-menopausal hormone therapy, injectable contraceptives.
•Known endocrinological disorders potentially leading to hypo- or hypermetabolism, untreated or treated for ≤ 1 month : disorders of thyroid gland, adrenal glands...
•Patients under weight loss drugs : GLP1 agonists, orlistat

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 22, 2025Terms

Trial snapshot

StatusRECRUITING

Phase—

Enrollment157

Start dateFeb 2025

Last updatedMay 22, 2025

Condition

Chronic Kidney Diseases Cachexia

Locations shown

Cliniques universitaires Saint-Luc

Brussels

UCLouvain

Brussels

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 22, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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