patients ≥ 18 years with malignant melanoma (Stage IIb - IV) receiving adjuvant or palliative immunotherapy or targeted therapy
patients with ECOG level 0-2
patients already on the same treatment protocol for at least 3 months and no more than 9 months
sufficient knowledge of German
completed and signed written consent form and completed medical history form
medical clearance for the exercise program and performance diagnostics
ability to participate in the exercise program
willingness to visit the study hospital for training sessions and examinations
You may not be if
confirmation of contraindications for physical exercise by the attending physician (e.g. fracture risk in the case of bone metastases)
untreated, symptomatic, known brain metastases
severe neurological or cardiac impairment according to ACSM criteria
confirmation of respiratory insufficiency by the attending physician
life expectancy less than 3 months
physical or mental conditions that would not allow implementation of the exercise program or study protocol
excessive physical activity (i.e. \>150 minutes/week of moderate to intense physical activity and systematic intense strength/endurance training at least twice a week for one hour)