Loading clinical trials...

The 'Bone-Brain' Crosstalk Mechanism of Subchondral Bone Nociceptive Sensitization Activating SPP1-Positive Microglia in the vlPAG Region Elucidates the Theoretical Connotation of Treating Knee Osteoarthritis Based on Kidney Differentiation | Clinical Trials | Clareo Health

Back to clinical trial search

Not Yet RecruitingNCT06977282

The 'Bone-Brain' Crosstalk Mechanism of Subchondral Bone Nociceptive Sensitization Activating SPP1-Positive Microglia in the vlPAG Region Elucidates the Theoretical Connotation of Treating Knee Osteoarthritis Based on Kidney Differentiation

The aim of this observational study is to investigate the relationship between pain severity and alterations in bone-derived and brain-derived signaling molecules (including serum neurotransmitters an...

Lead sponsor: Jinchao Xu•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Related studies

RECRUITING

Evaluation of Musculoskeletal Aging and Related Disorders Via Advanced Clinical Imaging

NCT07474571 · Osteoarthitis, Osteoporosis

Not Yet RecruitingNA

PRP Injection Into the Sacroiliac Joint After Ipsilateral THA: Effects on Early Recovery and Function (SIJ-THA Randomized Trial)

NCT07498660 · Osteoarthitis, Sacro Iliac Joint Pain, and more

COMPLETED

Screening Anxiety and Depression Among Patients with Chronic Musculoskeletal Pain Within Physiotherapy Practices

NCT06785883 · Osteoarthitis, Fibromyalgia, and more

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 18, 2025Terms

Trial snapshot

StatusNOT_YET_RECRUITING

Phase—

Enrollment120

Start dateJun 2025

Last updatedMay 18, 2025

Condition

Osteoarthitis

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 18, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions