Antoine LEFRERE

CONTACT

Lead Sponsor

Assistance Publique Hopitaux De Marseille

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

No

•Presence of bipolar disorder according to DSM-5 criteria
•Able to freely give and sign consent
•Affiliated or beneficiary of a health insurance plan
•Previous participants in the NEMO study (2022-A00353-40)
•For the "neurodevelopmental bipolar" (ND-BP) group: presence of a neurodevelopmental burden score in the top 5, as assessed in the NEMO project (NCT05674019).
•For the "non-neurodevelopmental bipolar" group (TB): presence of a neurodevelopmental load score of 0, or in the lowest 5, as assessed in the NEMO project.

•\- Presence of a severe symptomatic or unstable physiological or medical condition (including pregnancy)
•History of psychiatric illness (stable or not), schizophrenia or any other pathology likely to interfere with bipolar disorder
•History of severe head trauma (GCS\<8 at time of trauma)
•Presence of a neurological disorder affecting central nervous system function
•Presence of moderate to severe substance use disorders (\>=4/11 as defined in DSM-5), with the exception of tobacco use disorders.
•The volunteer is under court protection or guardianship
•It proves impossible to give the volunteer informed information, or the volunteer refuses to sign the consent form.
•Insufficient command of the French language to complete evaluations

Related studies

NCT07589647 · Bipolar Disorder (BD)

NCT06920940 · Bipolar Disorder (BD), Bipolar Disorder NOS, and more

NCT06488573 · Bipolar Depression, Bipolar Disorder (BD)

NCT07404085 · Bipolar Disorder (BD), Depression - Major Depressive Disorder, and more

NCT07329257 · Baker Gordon Syndrome, Rare Neurodevelopmental Conditions, and more

Analysis of Early Neurodevelopmental Alterations in Bipolar Disorder Based on Cortical Organoid Models