Experimental radiosurgery of the prostate with 3 fractions each with 9.5 -10.5 Gy (total application rate of 28.5-31.5 Gy) based on risk grading.
Planned visits are: Baseline, visits at every radiation day and four follow ups (4-6 weeks, 3 months, 6 months and one year after last day of radiation).
Age
18–any
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Localised, histopathologically confirmed Prostate Cancer (cT1-T2c N0 M0)
Gleason-grade ≤7, ISUP Grade Group 1-3
Guideline-based staging
Age ≥ 18 years
PSA \< 20 ng/ml
Volume of the prostate \< 80 cm³
IPSS-Score ≤ 12
Written informed consent
You may not be if
History of prior pelvic radiotherapy
Previous transurethral resection, laser enucleation or prostate ablation
Contraindication to MRI or Fiducial marker implantation (e.g. gold allergy)
Relevant comorbidity thought to adversely affect treatment compliance
Legal incapacity or lack of informed consent
Clareo Health | Hypofractionated Radiosurgery for Localised Prostate Cancer (HYPOSTAT-III)
