Efficacy and Safety of a Solution for Endoscopic Mucosal Resection of Colonic Lesions

Exclusion Criteria

• •Patients with documented allergy to any of the components of the mucosectomy solution or drugs used in sedation.
• •Pregnant women.
• •Patients on contraceptive treatment or post-menopausal.
• •Hematological disorders with uncorrected coagulation abnormalities, with an INR \>= 1.5, or patients undergoing active treatment with antiplatelet or anticoagulant drugs.
• •Patients with intestinal perforation or obstruction, toxic megacolon, diverticulitis, or inflammatory bowel disease.
• •Patients with previous partial resection or pending resection.
• •Patients with lesions classified as Paris type III and/or invasive intestinal carcinoma and/or metastases. Patients with previous treatment of the lesion (radiotherapy, endoscopic, surgical, chemotherapy).
• •Patients included in another study during the previous month.
• •Conditions that, in the medical judgment, contraindicate polyp removal.
• •Absence of a signed informed consent, non-acceptance, or contraindication of surgical or anesthetic techniques (Patients with ASA status: High anesthetic risk (ASA score \> 3)) and difficulty in the patient's understanding of the conditions of the endoscopic procedure.
• •Endoscopic appearance of invasive malignancy.