Participant must provide written informed consent prior to any clinical investigation-related procedures.
Age ≥ 18 years
Planned lower extremity catheter-based revascularization for Rutherford 4 through 6 chronic limb-threatening ischemia (Table 1)
Stenotic (\>=70% stenosis by visual estimate) or occlusive lesion in an infrapopliteal artery (anterior tibial, peroneal, or posterior tibial) by angiography
Target lesion up to 25cm in length by angiography
You may not be if
Participation in another clinical investigation that has not yet completed its primary end point.
Incapacitated individuals, defined as persons who are mentally ill, mentally handicapped, or individuals without legal authority, are excluded from the study population.
Female subjects of childbearing potential unless negative pregnancy test or contraceptive use
Bilateral critical limb ischemia
Planned bilateral vascular intervention
Lack of reconstitution of foot runoff vessels at ankle joint
Planned below-the-ankle intervention after completion of diagnostic angiography
Planned suprainguinal intervention -\>=5cm with at least 50% stenosis of the above knee femoro-popliteal artery
