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Melatonin for Patients With Chronic Low Back Pain | Clinical Trials | Clareo Health

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RECRUITINGPhase 3NCT06859957

Melatonin for Patients With Chronic Low Back Pain

Low back pain is one of the conditions causing more disability worldwide. The use of pain medications is substantial in patients with chronic LBP. But the efficacy of commonly used analgesics is modes...

Lead sponsor: Bart Koes•1 locations•View source on ClinicalTrials.gov

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Contacts

Prof. dr. B.W. (Bart) Koes

CONTACT

010-7035882 [email protected]

Sponsors

Lead Sponsor

Bart Koes

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•age 18-65
•understand and write Dutch
•LBP for 3 months or longer
•LBP must be present on 'most days' or 'every day' within the past 3 months
•LBP must limit life or work activities on 'some days', 'most days', or 'every day' within the past 3 months
•average LBP intensity of ≥4 on a 0-10 NRS in the past 7 days

Exclusion Criteria

•LBP resulting from a specific cause such as malignancy, fracture, lumbar radiculopathy and spinal stenosis
•Radiating pain into the leg that goes further (down) than the knee
•Inflammatory/autoimmune arthritis
•Severe physical or psychiatric co-morbidities
•Contraindications to melatonin

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 22, 2025Terms

Trial snapshot

StatusRECRUITING

PhasePHASE3

Enrollment240

Start dateApr 2025

Last updatedAug 22, 2025

Condition

Chronic Low-back Pain (cLBP)

Locations shown

Erasmus MC

Rotterdam

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 22, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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