Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sound Pharmaceuticals, Incorporated
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult males/females, 18-75 years of age at the time of enrollment.
Diagnosis of probable or definite Meniere's Disease by AAO-HNS Amended 2015 Criteria.
At least two of three active symptoms (fluctuating hearing; tinnitus; aural fullness; vertigo or dizziness) of Meniere's disease, within 3 months of study enrollment.
Type A tympanogram at screening.
Air conduction thresholds ≤ 90 dB at all tested frequencies (250-8000 Hz) in both ears.
Subject is willing and able to provide informed consent and perform study procedures and assessments per protocol.
Reproductive requirements
You may not be if
Current, or within 60 days prior to study enrollment, use of IV or intratympanic ototoxic medications such as chemotherapy including cisplatin, carboplatin, or oxaliplatin; aminoglycoside antibiotics including gentamicin, amikacin, tobramycin, kanamycin, or streptomycin; or loop diuretics including furosemide.
History of otosclerosis or vestibular schwannoma.
History of significant middle ear or inner ear surgery in the affected ear.
Conductive hearing loss with air-bone gap ≥15 dB, otitis media, or mixed hearing loss.
