Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Beijing Chao Yang Hospital
With
Capital Medical University
Peking University Third Hospital
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Must be at least 18 years old and have resided in Beijing for at least 6 months.
Must meet the diagnostic criteria for asthma as outlined in the 2023 GINA guidelines, have written evidence of variable airflow limitation, and have been receiving asthma treatment for at least 6 months.
Must meet one or both of the following criteria as defined in the 2023 GINA guidelines for uncontrolled asthma: poor symptom control (defined as an Asthma Control Questionnaire (ACQ-5) score of 0.75 or higher); frequent acute exacerbations (≥2 per year) requiring oral corticosteroids, or severe acute exacerbations (≥1 per year) requiring emergency or hospitalization.
Willing to undergo a multidisciplinary, multi-dimensional evaluation and sign an informed consent form.
Must meet the criteria for severe asthma as outlined in the 2023 GINA guidelines
You may not be if
Use macrolides within 4 weeks of the screening period
Use anti-IgE, anti-IL-5, or anti-IL-5R therapy within 4 weeks of the screening period
Use inhaled ICS + LABA + long-acting muscarinic antagonist (LAMA) within 4 weeks of the screening period
Be allergic to macrolides
Have a QTc interval prolongation of \>480ms
Take a medication that interacts with azithromycin to prolong the QTc interval or cause existing ECG abnormalities, which may lead to arrhythmias.
