Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects

Inclusion Criteria

• •Patient Cohort to be Recruited at the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna:
• •Age ≥ 18 years
• •Patients with a diagnosis of COPD of any severity (FEV1/FVC \< 0.7 after bronchodilation test)
• •Non-smokers according to ISS definition: patients who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
• •Signature of informed consent
• •Healthy Volunteer Cohort to be Recruited at the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna:
• •Age ≥ 18 years
• •Non-smokers according to ISS definition: subjects who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
• •Absence of comorbidities related to the study (COPD, solid tumors, leukemia) in medical history
• •Workers of the IRCCS AOU of Bologna, S. Orsola Polyclinic
• •Signature of informed consent
• •Patient Cohort to be Recruited at the Department of Medical Oncology, IRCCS AOU of Bologna:
• •Age ≥ 18 years
• •Patients with a diagnosis of lung neoplasm of any histotype and stage
• •Non-smokers according to ISS definition: patients who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
• •Signature of informed consent
• •Healthy Volunteer Cohort to be Recruited at the Department of Medical Oncology, IRCCS AOU of Bologna:
• •Age ≥ 18 years
• •Non-smokers according to ISS definition: subjects who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
• •Absence of comorbidities related to the study (COPD, solid tumors, leukemia) in medical history
• •Workers of the IRCCS AOU of Bologna, S. Orsola Polyclinic
• •Signature of informed consent
• •Patient Cohort to be Recruited at the Hematology Department (Hospital-University Company, Policlinico Riuniti di Foggia):
• •Age ≥ 18 years
• •Non-smokers according to ISS definition: patients who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
• •Patients with a diagnosis of leukemia of any type
• •Signature of informed consent
• •Healthy Volunteer Cohort to be Recruited at the Hematology Department (Hospital-University Company, Policlinico Riuniti di Foggia):
• •Age ≥ 18 years
• •Non-smokers according to ISS definition: subjects who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
• •Absence of comorbidities related to the study (COPD, solid tumors, leukemia) in medical history
• •Workers of the Hospital-University Company, Policlinico Riuniti di Foggia
• •Signature of informed consent