This proof-of-concept trial will be conducted with family members being monitored for a predisposition to breast and/or ovarian cancer linked to a BRCA1/2 gene mutation.
The study will be proposed to two sisters from the same sibling:
* one is a carrier of the genetic mutation
* and the other not,
Blood tests will evaluate the Mutation Burden cfMB
Age
30–50
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Female participant
Participant undergoing oncogenetic follow-up at the Centre François Baclesse
Participant belonging to a pair of related biological siblings
Within the sibling pair, one participant is a carrier of a hereditary predisposition linked to a BRCA1/2 mutation (case), and the other participant is not a carrier (control).
Participant between 30 and 50 years of age
Participant affiliated to a social security scheme
Participant having given her consent to participate by signing an informed consent form prior to any specific study-related procedure.
