Chemoablation Or Bladder Resection With Adjuvant Chemotherapy in Recurrent Non-Muscle Invasive Bladder Cancer

Exclusion Criteria

• •Known history of invasive tumour of the bladder (T1+)
• •Known history of CIS of the bladder
• •Previous MMC or BCG-treatment except for single instillations following previous TURBTs
• •Known allergy or intolerance to MMC
• •Solid tumour with suspicions of invasion
• •Tumour in the bladder neck or urethra
• •Suspicion of CIS (positive cytology with high-grade neoplastic cells combined with suspicious flat lesions seen at cystoscopy)
• •Small bladder volume (less than 100 ml) or incontinence
• •Prior radiation therapy to the pelvic area, as radiation affects the bladder function and instillation therapy is a suboptimal treatment for this patient group
• •Acute cystitis
• •Pregnancy or breast-feeding
• •Averse to using secure contraception with regard to men with partners and premenopausal women