National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
With
Vilnius University
Tomas Poskus, Faculty of Medicine, Vilnius University
Vilnius University Hospital Santaros Klinikos
Research Council of Lithuania
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Part One
Over 18 years of age.
Participants who agreed to participate in the study signed an informed consent form.
The Eastern Cooperative Oncology Group (ECOG) score ranges from 0 to 2.
Pathologically confirmed rectal adenocarcinoma.
Tumor up to 10 cm from the anus.
Magnetic resonance imaging (MRI) of the pelvis and computed tomography (CT) of the thorax and abdomen were performed to confirm the diagnosis.
cT1N1, T2-T3 N0 - 1, M0, MRF -, EMVI -.
Normal bone marrow function: blood leucocytes \> 3.5 × 10⁹/l, neutrophils \> 1.5 × 10⁹/l, platelets \> 100 × 10⁹/l.
Normal renal function: creatinine within 1,5 × normal.
Normal liver function: blood bilirubin levels within 1,5 times normal, AST, ALT levels within 2,5 times the upper limit.
Over 18 years of age.
Participants who agreed to participate in the study signed an informed consent form.
ECOG score between 0 and 2.
Pathological confirmed rectal adenocarcinoma.
Stage I to III rectal cancer confirmed.
The tumor is localized up to 12 cm from the anus.
Participants have received preoperative CRT or TNT or are in the planning stages of neoadjuvant treatment.
You may not be if
Prior ST or Ch.
Participants who have had a malignancy in the last 5 years, except for treatment for basal cell or squamous cell skin cancer or in situ cervical cancer.
ECOG status ≥ 3.
Distant metastases detected.
Participants with uncontrolled therapeutic or psychiatric conditions.
