The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled Trial
patients with peripheral lung nodules suspected of lung cancer based on CT scan (10mm≤size\<30mm);
patients requiring diagnostic bronchoscopy procedure to determine the benign or malignant nature of the lung nodule;
Patients who can understand the purpose of the trial, participate voluntarily and sign an informed consent form.
You may not be if
Inability or non-willingness to provide informed consent;
Endobronchial visible malignancy on bronchoscopic inspection;
Target lesion within reach of the linear EBUS scope;
Failure to comply with the study protocol;
Known allergy or risk factors for an allergic reaction to fluorescein;
Pregnancy or breast feeding;
Haemodynamic instability;
Refractory hypoxaemia;
Therapeutic anticoagulant use that cannot be withheld for an appropriate interval before the procedure;
Unable to tolerate general anaesthesia according to the anaesthesiologist;
Undergoing chemotherapy as several chemotherapies have fluorescent properties at the same wavelength (eg, doxorubicin).
Clareo Health | The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled Trial