Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Plaque and Gingivitis

Exclusion Criteria

• •Absence of visible clinical signs of periodontal disease, such as the presence of suppuration, dental mobility, and/or extensive attachment loss;
• •That received dental prophylaxis within 1 month prior to the Baseline visit;
• •Oral pathology or a history of allergy to testing products;
• •Subject using anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory medication or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study; to be defined by the dental examiner;
• •Subject participating in any other clinical study;
• •Subject pregnant or breastfeeding;
• •Subject allergic to oral care products, personal care consumer products, or their ingredients;
• •Extended use of antibiotics or therapeutic mouthwash (eg: Chlorhexidine) any time during the three months prior to entry into the study;
• •Ongoing use of medications known to affect the gingival tissues (i.e. calcium channel blockers, phenytoin, cyclosporine);
• •Current smokers and subjects with a history of alcohol or drug abuse;
• •Subjects with orthodontic appliances or presence of fixed or removable prosthodontics dentures that may interfere with the evaluations
• •An existing medical condition (eg: diabetic people) which prohibits eating or drinking for periods up to 4 hours.