The patient must have given their free and informed consent and signed the consent form
The patient must be a member or beneficiary of a health insurance plan
Diagnosis of depression according to DSM-5 criteria
Suspicion of a sleep disorder requiring polysomnographic screening
Score for IHSS items 3 and 4
* Score ≥ 1 for group with sleep inertia
No complaints of sleep inertia (score = 0 on IHSS items 3 and 4)
No excessive daytime sleepiness (Epworth Sleepiness Scale score ≤10),
No depressive symptoms (Hospital Anxiety Depression Scale score \< 8 on items 2, 4, 6, 8, 10, 12, 14).
You may not be if
The patient is participating in an interventional study
The patient is under safeguard of justice or state guardianship
Unweaned from the following medications for at least 5 half-lives prior to inclusion: wake-promoting or psychostimulant drugs (modafinil, methylphenidate, mazindol, amphetamine, pitolisant, solriamfetol, sodium oxybate), neuroleptics, hypnotics, antidepressants, anxiolytics, antiepileptics, budipine, dopamine agonist and antagonist antiemetics (except domperidone), opiates, gabapentin, pregabalin, benzodiazepines, Z-hypnotics (zolpidem and zopiclone), monoamine oxidase inhibitors, catechol-O-methyltransferase or sedative antihistamines.
Patients with central nervous system diseases: Parkinson's disease, mild cognitive impairment and dementia, progressive supranuclear palsy, multisystem atrophy, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, history of head trauma with loss of consciousness.
Patients with a malignant neoplastic disease requiring therapeutic treatment in the 12months prior to the screening visit
Other medical or psychiatric illnesses (with the exception of depression in he depression group) which, in the investigator's opinion, could interfere with the study.
History of suicide attempt (including failed attempt), or suicidal ideation in the past month
Chronic alcohol consumption or drug abuse in the previous 6 months
Sleep-wake circadian rhythm disorders and presence of sleep insufficiency according to ICSD-3 criteria
Pregnant, parturient or breast-feeding women.
Clareo Health | Study of Sleep Inertia in Major Depressive Disorder by the Psychomotor Vigilance Task
