Effect of G-CSF on MDSC and Cancer Stem-cells Interactions in Non-small Cell Lung Cancers (CIRCUIT)

Exclusion Criteria

• •Patient with a small cell lung carcinoma
• •Non-metastatic disease
• •Actionable mutation or genomic alteration in EGFR, ALK or ROS1
• •Corticosteroids \> 10 mg/j
• •Autoimmune disease
• •Active and uncontrolled HIV infection
• •Concomitant cancer
• •Pregnancy or lactating women
• •Psychiatric or medical conditions that prohibit the understanding and rendering of informed consent
• •Patient under a legal protection measure
• •Patient with a deprived liberty condition
• •Patient incapable of giving signed informed consent
• •Patient within the exclusion period for another clinical trial, or participating to another interventional trial within 30 days before the beginning of this project